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Data Mining Techniques : For Marketing, Sales, and Customer Relationship Management

Michael J. A. Berry

ToolData Mining Techniques : For Marketing, Sales, and Customer Relationship Management
Published: 05 April, 2004
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Author: Michael J. A. Berry

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How to Administer an Epinephrine Shot
The worst time to find out you're highly allergic to something is when your throat suddenly starts to swell shut. Slow the onset of anaphylactic shock by delivering a quick injection of epinephrine as a first aid measure. Modern devices make it easy, but it's best to be prepared, so learn the basics now by following our guide.<br style="clear: both;"/> <a href="http://www.pheedo.com/click.phdo?s=83f16bed2217e1a0d285b7a954a4b85a"><img alt="" style="border: 0;" border="0" src="http://www.pheedo.com/img.phdo?s=83f16bed2217e1a0d285b7a954a4b85a"/></a> <img src="http://www.pheedo.com/feeds/tracker.php?i=83f16bed2217e1a0d285b7a954a4b85a" style="display: none;" border="0" height="1" width="1" alt=""/><div class="feedflare"> <a href="http://feeds.wired.com/~f/wired/medtech?a=FEVVSK"><img src="http://feeds.wired.com/~f/wired/medtech?i=FEVVSK" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=mzV6Bk"><img src="http://feeds.wired.com/~f/wired/medtech?i=mzV6Bk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=UWQvsk"><img src="http://feeds.wired.com/~f/wired/medtech?i=UWQvsk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=5vGHNK"><img src="http://feeds.wired.com/~f/wired/medtech?i=5vGHNK" border="0"></img></a> </div><img src="http://feeds.wired.com/~r/wired/medtech/~4/370430556" height="1" width="1"/>


Scientists Create Universal Blood From Stem Cells
For the first time, scientists have made blood from embryonic stem cells, potentially providing a limitless and safe source of transfusions.<br style="clear: both;"/> <img alt="" style="border: 0; height:1px; width:1px;" border="0" src="http://www.pheedo.com/img.phdo?i=fbec00ac4f2c6bfba84e3a728ec9c804" height="1" width="1"/> <img src="http://www.pheedo.com/feeds/tracker.php?i=fbec00ac4f2c6bfba84e3a728ec9c804" style="display: none;" border="0" height="1" width="1" alt=""/><div class="feedflare"> <a href="http://feeds.wired.com/~f/wired/medtech?a=kjc6OK"><img src="http://feeds.wired.com/~f/wired/medtech?i=kjc6OK" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=XOPdNk"><img src="http://feeds.wired.com/~f/wired/medtech?i=XOPdNk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=TLH1Mk"><img src="http://feeds.wired.com/~f/wired/medtech?i=TLH1Mk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=JaHAAK"><img src="http://feeds.wired.com/~f/wired/medtech?i=JaHAAK" border="0"></img></a> </div><img src="http://feeds.wired.com/~r/wired/medtech/~4/369218316" height="1" width="1"/>


Olympic Age Controversy: Beyond The Reach of Science?
Scientists say pinning down chronological age isn't possible, though some countries are trying to find biomarkers to aid in their juvenile justice systems.<br style="clear: both;"/> <img alt="" style="border: 0; height:1px; width:1px;" border="0" src="http://www.pheedo.com/img.phdo?i=9204e204f10888d9ea6957cbab670b1f" height="1" width="1"/> <img src="http://www.pheedo.com/feeds/tracker.php?i=9204e204f10888d9ea6957cbab670b1f" style="display: none;" border="0" height="1" width="1" alt=""/><div class="feedflare"> <a href="http://feeds.wired.com/~f/wired/medtech?a=DafrVK"><img src="http://feeds.wired.com/~f/wired/medtech?i=DafrVK" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=a6Bqok"><img src="http://feeds.wired.com/~f/wired/medtech?i=a6Bqok" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=YBv9vk"><img src="http://feeds.wired.com/~f/wired/medtech?i=YBv9vk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=n9rIeK"><img src="http://feeds.wired.com/~f/wired/medtech?i=n9rIeK" border="0"></img></a> </div><img src="http://feeds.wired.com/~r/wired/medtech/~4/368351403" height="1" width="1"/>


Injured? Horsing Around With Stem Cells May Get You Back in the Saddle
<p>Doctors might soon be able to regrow injured muscles, tendons and bones without invasive surgery, simply by injecting a person's own stem cells into the site of an injury. Veterinarians are already doing it with injured horses, and research into human applications is well under way. </p> <p> The National Institutes for Health seem to think regenerating human muscle and bone using a person's own adult stem cells is nearly ready for prime time. Last week, the NIH announced to its staff that it's creating a bone marrow-stem cell transplant center within the NIH Clinical Research Center. </p> <p> Researchers at the NIH labs in Bethesda, Maryland, are already growing human muscle, cartilage and spinal disks in vitro. The tissue isn't mechanically sound yet, says lead researcher Rocky Tuan, but that will come with further work. </p> <p> "I have a piece of tissue that looks like a spinal disc, a sand bag, tough as nails on the outside and like sand on the inside," says Tuan, a Ph.D. and the senior investigator in the Cartilage and Orthopedics branch of the NIAMS. "The mechanical properties are lousy, but it's a beginning." </p> <p> While the use of stem cells harvested from human embryos has been getting the most media attention, scientists and doctors have also been working with adult stem cells that also have the ability to become one with their environment and to replicate as cells of their adopted tissue. Using adult stem cells -- grown inside the body or in the lab -- has become accepted in the veterinary community, and horses have benefited greatly. Researchers are working to bring those same benefits to humans, but there are still hurdles left to clear. </p> <p> The NIH project comes in part from what veterinarians have learned from injecting adult stem cells into valuable horses who've suffered injuries. In many cases, those horses' careers were saved when the stem cells regrew damaged tendons and ligaments. </p> <p> Rodrigo Vazquez, a Southern California veterinarian, has been using adult stem cells to regrow damaged muscles in horses for several years. It's a fairly common procedure in the veterinary arena, and the results are impressive: One of Vazquez's patients is participating in this year's Olympics Dressage events; another is a prize-winning jumper. </p> <!--pagebreak--> <p> The procedure is simple and straightforward. Inside a surgical suite at his equine hospital, Vazquez removes blood full of adult stem cells from the sternum of the anesthetized horse. </p> <p> Then he rolls his stool to the other end of the horse, where ultrasound data has helped guide needles into the exact areas on the rear leg where the beautiful horse's ligaments are torn. He injects the stem cells into those spots. </p> <p> "A few years ago, these injuries were career-ending," Vazquez says. Not any more. "In a month, the torn tissue will be completely regrown and healed." </p> <p> Vazquez would like to put himself in his patients' place. He has had surgery several times for spinal injuries he incurred while lifting horses. Human medicine, unable to regrow or heal the injured spine, simply fuses the bone and tissue through a surgical procedure. At best, the surgery relieves some of the pain and restores some mobility. But it's not a true repair. </p> <p> "I wish I could have had a procedure like this," Vazquez says of the treatment he gives horses. "This will lead to human treatments, but they can't move as fast as we can." </p> <p> Tuan, who is using stem cells to cultivate experimental tendons and disks in his lab, thinks it's about time to look to treating humans. </p> <p> An emerging body of scientific studies from all over the world -- including a cardiac study under way in Miami and a pediatric ACL (anterior cruciate ligament) study at the Harvard-affiliated Children's Hospital of Boston -- is showing that using a patient's own stem cells can prompt the growth of new muscle, from the knee to the heart. And the precursor step, using platelet-rich plasma for injuries, is on the verge of becoming mainstream. </p> <p> Adult stem cells, particularly mesenchymal cells that come from muscle, bone and fat, are cells with a powerful ability to replicate and not a lot of personal identity. They easily take on the characteristics of surrounding cells and they tend to grow quickly once they get there. Ultrasounds of Vazquez's horses, for example, show regeneration of muscle in four to six weeks. </p> <div id="embed_wide"> <div id="pic"> <a href="#" onclick="launchWindow('/imageviewer/?imagePath=/images/article/full/2008/08/cartilage_like_tissue_630px.jpg&imageCaption=%3Cem%3EJon+Snyder%2FWired%3C%2Fem%3E&image Credit=','1092','827')" title=""><img src="/images/article/full/2008/08/cartilage_like_tissue_630px.jpg" alt=""></a> <div id="caption"> The final product is this cartilage-like tissue grown around the scaffolding by NIH scientists. Tuan says the tissue resembles the human version, but may not be mechanically sound -- yet. <br> <em>Courtesy NIAMS</em> </div> </div> </div> <p> Adult stem cells can be found all over the body, in bone and marrow. Tuan says they're also found in tonsils and in the placenta and umbilical cord, which suggest that the discarded body parts can be stored for later use. </p> <p> Because researchers are using autologous cells -- from the patient's own body -- the research is not controversial. No one has challenged the ethics or funding of adult stem cell research the way embryonic stem cell studies have been challenged. And because adult stem cells are native to the patient's own body, the chances of a patient rejecting them are slim to none. </p> <!--pagebreak--> <p> Tuan and his team have been able to coach adult stem cells to form muscle and disks using goo from the small intestine and a polymer scaffold to tell cells how to grow. But, he cautions, the primitive structures aren't ready to go into humans. </p> <p> "After a few weeks (of lab growth), it will turn into something that resembles a tendon, but it has to be the mechanical equivalent and we don't know that we're there," Tuan says. "Stem cells are very promising, but what they do for horses may not work so well for humans because humans are the hardest animal to rebuild." </p> <p> Once they're perfected, Tuan sees a day when the tendons will change the dreaded surgery for torn anterior cruciate ligaments that sideline up to a quarter-million people in the United States and Canada every year. </p> <p> "Often, that injury is a complete tear -- the ligament is snapped in two and the ends ball up and even if you untangle them and pull them together, they won't heal," he says. "So they take part of the patella tendon, which is short and tough, and stretch it and staple it to the bones. So not only is your ACL not working too well and you have to stretch it out, but your knee hurts like crazy." </p> <p> "If we can learn to grow a tendon that works right, or figure out how to make the ACL heal back together, we can save a lot of people a lot of pain," he says. </p> <p> In fact, doctors are already treating people with adult stem cells. Bone marrow transplants for cancer patients are basically stem cell therapy. But the marrow often comes from other people, and its primary purpose is to boost a weakened immune system, not to generate tissue. </p> <p> And treating with platelet-rich plasma -- a blood product made by spinning a patient's blood in a centrifuge to concentrate the platelets -- is already in limited use and is becoming more widely accepted as a safe therapy. PRP is routinely used in cardiac surgery, where applying it to a cut sternum before closing has been shown to cut the infection rate in half. The plasma has growth factors that also promote healing. </p> <p> "PRP helps recruit stem cells to the injury," says Dr. Allan Mishra, who has used PRP on its own and as part of surgery in sports injuries -- including treating tennis elbow and getting Stanford football player James McGillicuddy's patellar tendon to heal after his second surgery. "The body knows how to heal itself -- we're speeding up and concentrating the process." </p> <p> Last year, Mishra wrapped up a study where he used platelet-rich plasma to treat the 20 worst tennis-elbow injuries he'd culled from more than 100 volunteers. "Ninety-three percent got better with a single injection and stayed better for two years," Mishra says. </p> <p> The treatments are about one-tenth of the cost of surgery, or about $2,000 to $2,500, he says. The patient's blood is drawn, centrifuged by a specialist called a perfusionist, and injected, all in one visit. "I will guess that five years from now, insurance companies won't authorize surgery until the patient has tried and failed at PRP." </p> <p> The obvious next step is to isolate the stem cells and send them to work, both inside and outside the body, researchers say. "PRP is reparative. Stem cells are regenerative," says Angela Nava, a perfusionist who processes both animal and human blood for PRP, stem cell and other procedures. </p> <p> But getting from animals to humans is going to take a lot more research, according to Dr. Thomas Rando, an associate professor of neurology at Stanford University School of Medicine. Rando studies the body's signaling systems that tell stem cells what to do. </p> <p> "We don't always know how stem cells, when injected into some tissues, work their magic," Rando said. "Veterinarians don't go back and study the horse's tendons to figure out what the stem cells did to promote healing." </p> <p> "There are all kinds of ways stem cells could work. If we could understand how they are actually promoting better function of the tissue, we might be able to further improve their therapeutic effects," he adds. </p> <p> Stem cell treatment is not without risks, researchers say. The worst-case scenario is that the stem cells could cause cancer -- or become cancerous themselves. </p> <p> "You're putting in cells that want to grow. That has to be under control," Rando says. "Or we can end up with cancer." </p> <p> Tuan also says that researchers don't entirely trust stem cells and their ability to adapt and grow. </p> <p> "There's a nagging feeling that there's a cancer stem cell, that when it's agitated by exposure to carcinogens or radiation or something, it goes nuts, and that we can't identify it from the other stem cells," he says. "How do you find this bad boy and pull him out? </p> <p> "And there's a nagging worry it's the same cell. We only know these cells by what they've done, and by the time they've become cancer, it's too late." </p><br style="clear: both;"/> <img alt="" style="border: 0; height:1px; width:1px;" border="0" src="http://www.pheedo.com/img.phdo?i=110d956a892b71e0185f81169e2f0b97" height="1" width="1"/> <img src="http://www.pheedo.com/feeds/tracker.php?i=110d956a892b71e0185f81169e2f0b97" style="display: none;" border="0" height="1" width="1" alt=""/><div class="feedflare"> <a href="http://feeds.wired.com/~f/wired/medtech?a=519dgK"><img src="http://feeds.wired.com/~f/wired/medtech?i=519dgK" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=YqA2sk"><img src="http://feeds.wired.com/~f/wired/medtech?i=YqA2sk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=n4P9Ck"><img src="http://feeds.wired.com/~f/wired/medtech?i=n4P9Ck" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=MHIDSK"><img src="http://feeds.wired.com/~f/wired/medtech?i=MHIDSK" border="0"></img></a> </div><img src="http://feeds.wired.com/~r/wired/medtech/~4/367766936" height="1" width="1"/>


Cheats of Strength: 10 Next-Gen Olympic Doping Methods
<p>While the International Olympic Committee is busy trying to catch today's performance enhancers, athletes are already looking for the next big boost that will give them the edge in 2012. </p> <p> Most of the positive doping tests in Beijing -- and the IOC president estimates there will be as many as 40 -- will likely be for steroids and the blood-boosting hormone erythropoietin, known as EPO. </p> <p> But the future of doping could get a lot more complicated. Here are some of the most promising -- or threatening, if you're the World Anti-Doping Agency -- candidates for the next Olympics. </p> <p> <strong>Use your genes to grow more muscle</strong> </p> <p> Manipulating genes to block naturally occurring muscle-growth inhibitors could allow athletes to boost their muscle mass. A lot. </p> <p> In tests on mice, blocking the protein myostatin gave the mice up to 60 percent more lean muscle mass. Even more promising, Johns Hopkins' Se-Jin Lee recently found that overproduction of one myostatin inhibitor pumps the mice up even more: up to 81 percent in females and a whopping 116 percent in males. Results of human clinical trials are pending. </p> <p> Complicating the picture, particularly for WADA, is a small number of people with naturally inhibited myostatin who will have to be distinguished from the dopers somehow. </p> <p> <strong>Pop a blood-boosting pill</strong> <p> Who wouldn't love a pill that delivers the same record-breaking benefits of synthetic EPO without the hassle of injections or getting caught? </p> <p> Clinical trials are under way for a pill that tricks the body into thinking blood-oxygen levels have dropped, causing it to produce more red blood cells, thus improving muscle endurance. </p> <p> When blood-oxygen levels drop, hypoxia-inducible factor, or HIF, kicks in to stimulate red blood cell production. Once oxygen is back to normal, the HIF breaks down and cell formation stops. The drugs, known as HIF stabilizers, stop the breakdown and keep blood production up. </p> <p> Some suspect athletes may already be using HIF stabilizers, but the health risks are unknown. </p> <!--pagebreak--> <p> <strong>Grow more blood vessels</strong> </p> <p> If you don't mind injections directly into your heart and limbs, vascular endothelial growth factor may be for you. VEGF causes new blood vessels to grow, which in theory could move more oxygen and nutrients between muscles, lungs and the heart with less effort. So more effort could be expended on athletic performance. VEGF gene therapy could potentially help patients with heart and arterial diseases form new blood vessels, keeping them alive and avoiding amputation. But it's not a simple hack, and a failed gene-doping test isn't the only risk. Unregulated VEGF-induced vessel growth appears to also promote tumor growth and metastasis. </p> <p> <strong>Feel less pain, get more gain</strong> </p> <p> Athletes know how to suffer. Raise an athlete's pain threshold, and suffering will occur at a higher level of exertion. </p> <p> Tests on rats suggest that injecting the beta-endorphin gene into spinal fluid through a spinal tap causes the body to release its own painkilling endorphins. Pain signals get blocked before they reach the brain, without the sleepiness and cloudiness associated with morphine and other painkilling opioids. </p> <p> Raising an athlete's pain threshold may improve performance, but it may also cause them to ignore warnings of overexertion and injury. </p> <p> <strong>Beef up specific muscles</strong> </p> <p> Say you're a cyclist who wants powerful legs but a light upper body so you don't have to haul the extra weight when riding uphill. Or a tennis player who needs a bit more shoulder muscle. Injecting insulin-like growth factor, or IGF-1, into specific muscles sparks those muscles to grow while avoiding the full-body muscle growth usually associated with IGF-1. Physiologist H. Lee Sweeney at the University of Pennsylvania discovered this while looking for a treatment for muscle-wasting that avoids side effects from unwanted growth, such as cancer and heart enlargement. The targeted therapy may also make IGF-1 harder to detect in a doping test. Sweeney estimates that since his research was published, half of his e-mails are from athletes. He has worked with WADA, but others developing similar techniques may not. </p> <p> <strong>Get more muscles, fewer zits</strong> </p> <p> Want the muscle-building benefits of steroids without the testicle-shrinking, moob-growing, acne-popping side effects? That's the promise of selective androgen receptor modulators. </p> <p> SARMs bind to specific tissues, such as muscle and bone. Unlike some steroids, they don't indiscriminately also bind to prostate, liver and other tissues. And SARMs come in a pill. No needles or skin patches. </p> <p> These pills could be a boon to people suffering from muscle-wasting diseases and for athletes concerned about health risks associated with steroids. Sound too good to be true? Perhaps: A test to detect SARMs may be ready before the drugs are widely available. WADA won't tell until they catch an athlete. </p> <p> <strong>Fill up with new blood substitutes</strong> </p> <p> With EPO and blood transfusions increasingly detectable, athletes could return to blood substitutes for an extra hit of oxygen. Several athletes reportedly used substitutes in the past, and one cyclist may have almost died as a result. </p> <p> Some new substitutes could have similar problems. A report in the <cite>Journal of the American Medical Association</cite> in April <a href="http://jama.ama-assn.org/cgi/content/full/299/19/2304">criticized blood substitutes</a> such as PolyHeme and Hemopure for causing heart attacks and deaths in test subjects. But there are alternatives. Oxygen Biotherapeutics claims their experimental substitute, Oxycyte, carries oxygen 50 times more efficiently than natural blood without the risks of older substitutes. And Dendritech patented a blood substitute built from 3-D nanoparticles that the company builds in precise oxygen-carrying shapes. At least some blood substitutes may be easy to detect, but there are rumors the test isn't regularly used. </p> <!--pagebreak--> <p> <strong>Take a next-gen EPO</strong> </p> <p> At the Tour de France in July, Ricardo Ricco got caught using a new EPO-like blood booster, CERA, recently released by Roche. </p> <p> Before CERA was on the market, the pharmaceutical giant cooperated with WADA to have a test ready to trap cutting-edge dopers like Ricco, a sign that WADA is catching up to, and perhaps even staying ahead of, dopers.</p> <p> Or it's a sign that WADA needs help developing tests to detect each EPO variant, a tall order considering EPO and related drugs make up a $12 billion market. There are also dozens of EPO-stimulating agents available or in the works around the world. </p> <p> <strong>Pump up your muscle fiber</strong> </p> <p> Athletes already have more fatigue-resistant muscle fibers than couch potatoes. But new research shows they may be able widen that gap further by boosting levels of the gene responsible for adding new fibers. </p> <p> Recently, researchers at the Salk Institute in San Diego found that an existing medication, called GW1516, raises the levels of this gene, resulting in a 68 percent endurance improvement in fit mice. </p> <p> The Salk researchers are working with WADA on a test to detect use of GW1516. But several other drugs are known to manipulate the muscle-fiber genes, and others are believed to do the same. A test to detect this type of gene doping would need to cover a lot of uncharted territory. </p> <p> <strong>Lastly, use mustard?</strong> </p> <p> Athletes turned off by the latest biotech breakthroughs can try this recipe: Strip down and rub mustard oil all over your body. </p> <p> While exploring the role skin plays in the production of red blood cells, Randy Johnson's team of researchers at UC San Diego found that <a href="http://tinyurl.com/5un822">rubbing mustard oil on mice</a> caused spikes in natural EPO production, and that led to increased red blood cell levels. </P> <p> It's unclear how much mustard oil a human athlete would need to enhance performance, or how much mustard oil could lead to strokes and heart attacks. </P> <p> With all the crazy, complicated doping schemes out there could the journey to the top of the podium simply require a trip to the grocery store? </p><br style="clear: both;"/> <a href="http://www.pheedo.com/click.phdo?s=b6a9e2b9ff18571c5bb1901a2837a3ce"><img alt="" style="border: 0;" border="0" src="http://www.pheedo.com/img.phdo?s=b6a9e2b9ff18571c5bb1901a2837a3ce"/></a> <img src="http://www.pheedo.com/feeds/tracker.php?i=b6a9e2b9ff18571c5bb1901a2837a3ce" style="display: none;" border="0" height="1" width="1" alt=""/><div class="feedflare"> <a href="http://feeds.wired.com/~f/wired/medtech?a=GQemuK"><img src="http://feeds.wired.com/~f/wired/medtech?i=GQemuK" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=GYPj3k"><img src="http://feeds.wired.com/~f/wired/medtech?i=GYPj3k" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=5m40Ok"><img src="http://feeds.wired.com/~f/wired/medtech?i=5m40Ok" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=W3LlfK"><img src="http://feeds.wired.com/~f/wired/medtech?i=W3LlfK" border="0"></img></a> </div><img src="http://feeds.wired.com/~r/wired/medtech/~4/365257824" height="1" width="1"/>


Memory Disruption Could Aid Addicts
Scientists have reduced the drug-seeking behaviors of cocaine-addicted rats by disrupting the memories they associate with getting high.<br style="clear: both;"/> <img alt="" style="border: 0; height:1px; width:1px;" border="0" src="http://www.pheedo.com/img.phdo?i=9936288e0b2ec98d09474fa01722f25a" height="1" width="1"/> <img src="http://www.pheedo.com/feeds/tracker.php?i=9936288e0b2ec98d09474fa01722f25a" style="display: none;" border="0" height="1" width="1" alt=""/><div class="feedflare"> <a href="http://feeds.wired.com/~f/wired/medtech?a=2BOIKK"><img src="http://feeds.wired.com/~f/wired/medtech?i=2BOIKK" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=br9Nwk"><img src="http://feeds.wired.com/~f/wired/medtech?i=br9Nwk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=82WJtk"><img src="http://feeds.wired.com/~f/wired/medtech?i=82WJtk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=uVon6K"><img src="http://feeds.wired.com/~f/wired/medtech?i=uVon6K" border="0"></img></a> </div><img src="http://feeds.wired.com/~r/wired/medtech/~4/363414682" height="1" width="1"/>


3 Smart Things About Sunburn
<!-- pageType= magazinesmall slug= st_3smart section= medtech subsection= health headline= 3 Smart Things About Sunburn --> <p><strong>1</strong> Early hominids may have developed a sensitivity to UV rays for the good of the species. Based on a study using blood plasma, just an hour in direct sunlight could cause a 30 to 50 percent drop in folate levels &mdash; and low folate is linked to both abnormal sperm and birth defects. Good news for nerds: It's survival of the palest!</p> <p><strong>2</strong> World War II sailors were early adopters of sunscreen. The zinc oxide they smeared on their noses served to reflect and scatter UV light. Today's lotions have added organic compounds that absorb UV energy and dissipate it as heat.</p> <p><strong>3</strong> The sun isn't all evil. It stimulates your skin to produce vitamin D, and one study suggests that 1,000 IUs of D per day reduces your risk of certain cancers by up to 50 percent. But that's not a free pass to bake: More than 15 minutes of exposure daily over 40 percent of your body might just be an invitation to skin cancer.</p><br style="clear: both;"/> <img alt="" style="border: 0; height:1px; width:1px;" border="0" src="http://www.pheedo.com/img.phdo?i=843be8efd716fd47e418a81462247d64" height="1" width="1"/> <img src="http://www.pheedo.com/feeds/tracker.php?i=843be8efd716fd47e418a81462247d64" style="display: none;" border="0" height="1" width="1" alt=""/><div class="feedflare"> <a href="http://feeds.wired.com/~f/wired/medtech?a=zMjkOK"><img src="http://feeds.wired.com/~f/wired/medtech?i=zMjkOK" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=tbo3Wk"><img src="http://feeds.wired.com/~f/wired/medtech?i=tbo3Wk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=UdHYNk"><img src="http://feeds.wired.com/~f/wired/medtech?i=UdHYNk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=c71uJK"><img src="http://feeds.wired.com/~f/wired/medtech?i=c71uJK" border="0"></img></a> </div><img src="http://feeds.wired.com/~r/wired/medtech/~4/362589689" height="1" width="1"/>


Video: Emergency Room Stroke Exam with a Webcam
Doctors in rural ERs use webcams to get expert opinions on stroke patients. A study says that this technology helps them make the right decision.<br style="clear: both;"/> <img alt="" style="border: 0; height:1px; width:1px;" border="0" src="http://www.pheedo.com/img.phdo?i=4c870136f404ac2584f53fb8d5c46f74" height="1" width="1"/> <img src="http://www.pheedo.com/feeds/tracker.php?i=4c870136f404ac2584f53fb8d5c46f74" style="display: none;" border="0" height="1" width="1" alt=""/><div class="feedflare"> <a href="http://feeds.wired.com/~f/wired/medtech?a=N6rXRK"><img src="http://feeds.wired.com/~f/wired/medtech?i=N6rXRK" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=7B6oQk"><img src="http://feeds.wired.com/~f/wired/medtech?i=7B6oQk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=I5NRsk"><img src="http://feeds.wired.com/~f/wired/medtech?i=I5NRsk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=2fqwCK"><img src="http://feeds.wired.com/~f/wired/medtech?i=2fqwCK" border="0"></img></a> </div><img src="http://feeds.wired.com/~r/wired/medtech/~4/361233390" height="1" width="1"/>


Updata: Dire Prognosis for Once-Promising Artificial Blood
<!-- pageType= magazinesmall slug= st_fakeblood section= medtech subsection= health headline= Updata: Dire Prognosis for Once-Promising Artificial Blood authorName= Katharine Gammon creditType= photo credit= Suede --> <p>It "doesn't look like something you'd want dripping into your veins," wrote Wil McCarthy in the August 2002 issue of <cite>Wired</cite>. At the time, he had no way of knowing just how right he was about Hemopure, the artificial blood that seemed so promising. It was universally compatible and had a three-year shelf life (unrefrigerated). But a recent meta-analysis of trials on several substitutes &mdash; including Hemopure &mdash; contains some gory results. Turns out, the fake bloods scavenge nitric oxide, causing vasoconstriction; patients who get them are 2.7 times more likely to have a heart attack and 30 percent more likely to die. A <cite>Journal of the American Medical Association</cite> editorial has called for a halt to trials. </p><br style="clear: both;"/> <img alt="" style="border: 0; height:1px; width:1px;" border="0" src="http://www.pheedo.com/img.phdo?i=d6dbbc2ab0f762a68cc0222b64b3a4bd" height="1" width="1"/> <img src="http://www.pheedo.com/feeds/tracker.php?i=d6dbbc2ab0f762a68cc0222b64b3a4bd" style="display: none;" border="0" height="1" width="1" alt=""/><div class="feedflare"> <a href="http://feeds.wired.com/~f/wired/medtech?a=MPCRJK"><img src="http://feeds.wired.com/~f/wired/medtech?i=MPCRJK" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=uoqDtk"><img src="http://feeds.wired.com/~f/wired/medtech?i=uoqDtk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=p9qluk"><img src="http://feeds.wired.com/~f/wired/medtech?i=p9qluk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=Fp80XK"><img src="http://feeds.wired.com/~f/wired/medtech?i=Fp80XK" border="0"></img></a> </div><img src="http://feeds.wired.com/~r/wired/medtech/~4/357041261" height="1" width="1"/>


DNA Led the FBI to Anthrax Suspect
A government scientist reports that DNA taken from the bodies of people killed in the 2001 anthrax attacks helped lead investigators to Bruce Ivins, who oversaw the highly specific type of toxin in an Army lab.<br style="clear: both;"/> <a href="http://www.pheedo.com/click.phdo?s=7241b9983129d9d4dda8b9a096f8037c"><img alt="" style="border: 0;" border="0" src="http://www.pheedo.com/img.phdo?s=7241b9983129d9d4dda8b9a096f8037c"/></a> <img src="http://www.pheedo.com/feeds/tracker.php?i=7241b9983129d9d4dda8b9a096f8037c" style="display: none;" border="0" height="1" width="1" alt=""/><div class="feedflare"> <a href="http://feeds.wired.com/~f/wired/medtech?a=OZDoCK"><img src="http://feeds.wired.com/~f/wired/medtech?i=OZDoCK" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=srgLIk"><img src="http://feeds.wired.com/~f/wired/medtech?i=srgLIk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=C3wRRk"><img src="http://feeds.wired.com/~f/wired/medtech?i=C3wRRk" border="0"></img></a> <a href="http://feeds.wired.com/~f/wired/medtech?a=YnlfuK"><img src="http://feeds.wired.com/~f/wired/medtech?i=YnlfuK" border="0"></img></a> </div><img src="http://feeds.wired.com/~r/wired/medtech/~4/354761191" height="1" width="1"/>